Endocrine Abstracts

Idiopathic hypoparathyroidism (IHP) is an uncommon disease in which soft tissue calcifications may be seen. We report a case with IHP with asymptomatic hypocalcemia and features of ankylosing spondylitis (AS).Case: A 58-year-old male patient was referred to our department due to incidentally discovered hypocalcemia when admitted with blurred speech, gait and posture abnormalities. He had had a generalized convulsion 19 years ago. On physical examination,...

Introduction: Vitamin D deficiency may be an important predisposing factor for infections as well as autoimmune diseases in old individuals. Neutrophil/lymphocyte ratio (NLR), is a meaningful indicator of inflammation throughout the body. In this study we aimed to show, whether or not a relationship exists between vitamin D levels and NLR in patients older than 65 years.Materials and method: Data of 82 patients over 65 years of age was retrospectively ex...

Introduction: Apelin is an adipokine which plays a role in the regulation of glucose homeostasis. The relationship between apelin serum concentration and dysmetabolic conditions such as type 2 diabetes (T2D) is still controversial. The aim of our study was to investigate the association of apelin with gestational diabetes mellitus (GDM).Design and methods: This study was designed as a cross-sectional research that consecutively recruited subjects with GD...

Background: Primary empty sella is an anatomical term defining the herniation of subarachnoid space within the sella turcica without an underlying factor such as pituitary tumor, surgery, irradiation or trauma.Patients and methods: We retrospectively evaluated clinical, hormonal and radiological data of the patients with primary empty sella syndrome followed in our institution between 2001 and 2012.Results: Ninety-four patients (80...

Introduction: The growth promoting effects of GH and IGF1 has lead to increasing number of cancer surveillence studies in acromegaly so far. We herein aimed to present the prevalance of cancer in acromegaly patients followed in our institution.Patients and design: We retrospectively analyzed medical records of 151 patients with acromegaly (83 females) followed in our department from 2001 to 2012.Results: Overall, cancer was detecte...

Prediction of amputation would aid clinicians in the management of the diabetic foot infections. We aimed to assess the predictability of baseline and early post-treatment levels of acute phase reactants on the outcome of patients with diabetic foot infections.In this study, we included patients with infected diabetic foot ulcers who were hospitalized in Dokuz Eylul University Hospital between January 2003 and January 2008, of which data were collected p...

Women with a history of GDM may be at increased risk for future diabetes and cardiovascular disease. The aim of this study was to investigate the endothelium dependent hemostatic factors as well as the parameters of endothelial function and inflammation in women with pGDM.Eighty women with pGDM and 40 women (control) healthy women with normal glucose tolerance during pregnancy were studied. In all women, plasma glucose, insulin, C-peptid, lipid profile, ...

Introduction: Reduced creatinine clearance is related to an increased risk of diabetic foot ulcer development. Wound healing has been reported to be worse in diabetic patients with impaired kidney functions than general diabetic population. This study aimed to investigate the effect of creatinine clearance on the short term outcome of neuropathic diabetic foot ulcers.Materials and methods: Data from 147 neuropathic diabetic foot ulcer episodes were inclu...

Introduction: The incidence of diabetic foot in diabetics is 5-10%. We herein aimed to share a formerly undiagnosed diabetic patient presenting with crural infection.Case: A 48-year-old male patient, without a formerly known disease, presented to a local medical center due to spontaneously progressing ulceration on left leg. The ulcers did not improve with antibiotics in seven days and afterwards he was referred to our hospital. At admission, his plasma ...

Introduction: Continuous s.c. insulin infusion (CSII) therapy is a well documented treatment modality in type 1 diabetes mellitus (DM), but its usage in type 2 DM has not become prevalent so far. It may be a treatment alternative in severely insulin resistant type 2 diabetics recieving high doses of insulin. We present a type 2 diabetic patient that we had to shift from multiple dosage insulin (MDI) injection to CSII therapy due to the widespread echimosis at the insulin injec...